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  • Round Up: Top 5 Insights from the Summer 2018

    Here's our recap of the top Insight posts from the summer you might have missed! 1. Translational Microbiome Infographic Are you beginning your studies in the Microbiome and don't know where to start? Download and print out the Translational Microbiome at a Glance Infographic to... Read more

  • CASIS Announces Request for Proposals to Access Spaceflight Biospecimens

    Source: CASIS The Center for the Advancement of Science in Space (CASIS) recently announced a Request for Proposals (RFP) for investigators seeking to access biological specimens from its Rodent Research Reference Mission-1, Applications for Spaceflight Biospecimens. The BALB/c mice for the space flight are provided... Read more

  • Mouse Bioassay Helps Contain Botulism Outbreak

    Researchers from the Statens Serum Institut (State Serum Institute), Danmarks Tekniske Universitet (DTU, Technical University of Denmark) and Fødevarestyrelsen (Danish Veterinary and Food Administration) recently identified the source of a botulism outbreak that affected nine people in June 2018. The affected people became ill after... Read more

  • New Neurons

    On August 27, 2018, researchers at University of Szeged, Allen Institute for Brain Science, J. Craig Venter Institute, Hungarian Academy of Sciences, Illumina, Inc., and University of California, San Diego published a paper titled, Transcriptomic and morphophysiological evidence for a specialized human cortical GABAergic cell... Read more

  • Endocannabinoids Prevent Inflammation, Maintain Intestinal Homeostasis

    The inflammatory bowel diseases (IBD) are conditions regulated by a combination of genetic, immune and microbial factors. Although it is a normal component of host defense against pathogens, neutrophil influx to the intestinal lumen is also associated with severe pathology in IBD. In a recent... Read more

  • Investigating HIV-associated Liver Disease in dual-Humanized TK-NOG Mice

    As HIV-infected individuals live longer thanks to antiretroviral (ARV) therapies, chronic liver disease is becoming a major issue. Research into HIV-and ARV-induced hepatotoxicity has been limited due to the lack of relevant preclinical models. Humanized Mouse Models of HIV A recent study by Dagur et... Read more

  • IBD and Immune Checkpoint Modulators

    New research offers insights into the connection between regulatory T cells and ILC3-driven colitis, suggesting opportunities for checkpoint modulation therapies. Researchers at Merck and the University of Bern explored the role of FoxP3+ regulatory T cells (Treg cells) in innate lymphoid cell 3 (ILC3)-driven colitis.... Read more

  • Humanizing the gut microbiota of mice: Opportunities and challenges

    On August 8, 2018, Randi Lundberg, DVM, PhD published a review paper titled, Humanizing the gut microbiota of mice: Opportunities and challenges in the journal, Laboratory Animals. The author acknowledges the need for in vivo models to study the human microbiome's interaction with a biologically... Read more