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  • What is NASH?

    Recent reports indicate that non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are emerging public health threats. NAFLD is a common chronic liver disease, with estimates of incidence around 25% worldwide. NASH represents the more severe end of the NAFLD spectrum, with inflammation and... Read more

  • World Microbiome Day 2019

    World Microbiome Day is on June 27th this year. World Microbiome Day began in 2018 to demonstrate its emergence as a subject with global impact. That impact is being felt across a variety of disciplines including science, medicine, and nutrition. "World Microbiome Day aims to... Read more

  • Metastatic Prostate Cancer Modeling with Humanized Mice

    Prostate cancer will likely remain among the leading causes of cancer-related deaths in men until improved therapies for advanced metastatic disease become available. According to Dr. Steve Kregel, a postdoctoral researcher working with Dr. Arul Chinnaiyan at the University of Michigan, a key barrier to... Read more

  • Methods of Animal Model Identification

    Animal identification is a vital element in any research project requiring the use of animal models. The identification of an animal may be the only link to essential data, such as sex, genotype, study parameters, and results. Animal identification systems also assist with breeding record... Read more

  • Measles Outbreak Reaches Record Levels

    As of May 2019, the World Health Organization is reporting that the number of measles cases worldwide has quadrupled compared to the same time last year. In the US alone, there have been 1,022 cases thus far in 2019, making this the highest number of... Read more

  • Studying Genetic and Physiological Effects of Space Travel

    An article published recently in Science highlights the unique journey of two identical twins — Mark and Scott Kelly — who have enabled the study of extended space flight and the effects it has on the human body. Together, they spent a combined 574 days... Read more

  • Mouse Kidney Parvovirus (MKPV) - A New Mouse Pathogen

    The kidneys of immunodeficient mice infected with MKPV appear pale and shrunken on gross necropsy. Histology reveals significant fibrosis. Source: Roediger et al. Cell 20181. A consortium of researchers from Australia and the US has announced the discovery of a novel mouse parvovirus, named mouse... Read more

  • Animal Models and Infectious Disease

    Animal models play a critical role in studying a variety of infectious diseases, from lyme to influenza and salmonella, and selecting an appropriate model system for each is key. Both immunocompetent and immunodeficient mice have a role to play in infectious disease studies. Inbred Mouse... Read more